rolling circle mechanism

rolling circle mechanism
A mechanism of DNA replication in many viral DNAs, in bacterial F factors during mating, and of certain DNAs in gene amplification in eukaryotes. DNA synthesis starts with a cut in the + strand at the replication origin, the 5\' end rolls out and replication starts at the 3\' side of the cut around the intact circular DNA strand. Replication of the 5\' end (tail) takes place by the formation of Okazaki fragments.

Dictionary of molecular biology. 2004.

Игры ⚽ Поможем написать реферат

Look at other dictionaries:

  • rolling-circle mechanism — A mode of DNA replication in which the replication fork moves around a circular DNA molecule, displacing a strand to give a tail that is also copied to produce a new double stranded DNA …   Dictionary of microbiology

  • Rolling circle replication — describes a process of nucleic acid replication that can rapidly synthesize multiple copies of circular molecules of DNA or RNA, such as plasmids, the genomes of bacteriophages, and the circular RNA genome of viroids. Some eukaryotic viruses also …   Wikipedia

  • Rolling — is a combination of rotation (of a radially symmetric object) and translation of that object with respect to a surface (either one or the other moves), such that the two are in contact with each other without sliding. This is achieved by a… …   Wikipedia

  • Circle of forces — The circle of forces, traction circle, friction circle,[1] or friction ellipse[2][3][4] is a useful way to think about the dynamic interaction between a vehicle s tire and the road surface. In the diagram below we are looking at the tire from… …   Wikipedia

  • circle — 1. [TA] In anatomy, a ring shaped structure or group of structures, as formed by anastomosing arteries or veins, or by connected (communicating) nerves, 2. A line or process with every point approximately equidistant from the center. SYN:… …   Medical dictionary

  • Microviridae — Virus classification Group: Group II (ssDNA) Family: Microviridae Subfamily Gokushovirina …   Wikipedia

  • nucleic acid — /nooh klee ik, klay , nyooh /, Biochem. any of a group of long, linear macromolecules, either DNA or various types of RNA, that carry genetic information directing all cellular functions: composed of linked nucleotides. [1890 95; NUCLE(US) + IC;… …   Universalium

  • Transposable element — A bacterial DNA transposon Transposable elements (TEs) are sequences of DNA that can move or transpose themselves to new positions within the genome of a single cell. The mechanism of transposition can be either copy and paste or cut and paste .… …   Wikipedia

  • Hammerhead ribozyme — Taxobox | color=white name = Hammerhead Ribozyme image caption = Stylized rendering of the full length hammerhead ribozyme RNA molecule species = Catalytic RNAHammerhead RNAs are small self cleaving RNAs that have a conserved motif found in… …   Wikipedia

  • Avsunviroidae — The Avsunviroidae are a family of viroids. At present three members are known of. They consist of RNA genomes between 246 375 nucleotides in length. They are single stranded covalent circles and have intramolecular base pairing. All members lack… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”